Are Polynucleotides Safe?
In skin treatments, the polynucleotides used are typically extracted from natural, safe sources, such as fish, but they are purified to make sure they are compatible and safe for human use.
In medically trained, experienced hands polynucleotides are considered safe. Medical-aesthetic treatments do come with potential side effects and possible risks, such as bruising and swelling.
As polynucleotides are made of materials that are already found in the body, treatments using polynucleotides are generally well-tolerated; allergic reactions are rare. Nevertheless, it’s important to choose a provider that has the expertise and equipment to quickly deal with any possible risks when you have an aesthetic treatment.
Can Polynucleotides Migrate?
When exploring injectable treatments, migration of the product can be a concern. Essentially, migration is when an injectable product moves-or migrates-from the intended area.
When injected into the skin, polynucleotides intregrate into the targeted tissue. The polynucleotides begin to interact with the surrounding skin cells, hydrating the tissue, stimulating repair processes, and encouraging the regeneration of new skin cells.
Over time, the body naturally breaks down the polynucleotides, but their beneficial effects—such as increased hydration and improved collagen production—remain, but they don’t travel- or migrate- to other parts of the body.
Can This Help With Lines Under Eyes?
Polynucleotides can treat under the eyes. In fact, the PhilArt brand of polynucleotides that we use at our Hertfordshire clinic has formulated a polynucleotide treatment specifically for the eye area.
As polynucleotide treatment can help to hydrate your skin, promote cell regeneration, and stimulte collagen production, it can improve the texture and quality of the skin under your eyes.
The benefits of polynucleotides for under eye includes:
- Softened lines and wrinkles, as collagen and elasticity is boosted.
- Improved hydration, allowing the area look plumper and healthier.
- Reduction in puffiness and dark circles, because polynucleotides promote circulation and reduce inflammation.
Since the under-eye area is delicate area, polynucleotide injections are a good option to explore; they are generally safe and well-tolerated, with minimal risk of side effects. Polynucleotide treatment results can be subtle but effective, leaving your under-eye area looking refreshed.
Polynucleotides aren’t just used under the eyes however, they can be used to treat skin on the face, neck, and body. In fact, ageing hands are a popular area to have this skin treatment.
Before and After: What Type of Results Can Be Achieved
As mentioned earlier, the results of the polynucleotide treatment can be subtle and offer a natural-looking outcome ideal for those who don’t wish to look different, just the best version of themselves.
1. Scars on chin and upper lip. 3 sessions spaced every 4 weeks. Scars are greatly reduced, redness subsided, skin texture improved.

2. Scar on forehead. 4 sessions spaced every 3 weeks. Scar visibly reduced, as are forehead wrinkles. Bottom images show the reduction of redness and inflammation in the area.

3. Under eye circles. 3 sessions spaced every 3-4 weeks. Not only has the darkness below her eyes reduced but the upper eye lids are less heavy with more eye lid visible.

4. Ageing skin. 3 sessions spaced every 2-3 weeks. Ageing, thinning skin not only can appear crepey and lined but, particularly on the hands, can make the underlying structures more visible. For example, ligaments and blood vessels. The skin appears plumper and underlying structures less visible.

Surely salmon sperm can’t do all that?!